Back to Newsletter

Immunization Registries Briefing

ECBT Supports Continued Use of MMR Vaccine

Additional News Stories and Press Releases

National Infant Immunization Week

Gates Foundation Awards $18 Million Grant to Sabin Vaccine Institute

Upcoming Events

Back to Every Child By Two

Additional News Stories and Press Releases

American Academy of Pediatrics Says Evidence Confirms No Link Between Autism and Vaccines

WASHINGTON, April 6

In response to a U.S. House Government Reform Committee hearing today, the American Academy of Pediatrics wants to reassure parents that vaccines are the safest way to protect children against potentially devastating infectious diseases.

"What a tragedy it would be for any child to suffer the consequences
of a disease that could have been prevented by vaccination," AAP President Donald Cook, M.D., said.

If parents refuse to immunize their children, this country will see a
resurgence of epidemics of these diseases. The measles epidemic of
l989-1991 in this country affected more than 55,000 people; 11,000 were hospitalized and more than 120 died. A major cause of the epidemic was failure to vaccinate children on time at 12-15 months of age.

The congressional hearing is focusing on autism, including an unsubstantiated link to vaccines such as MMR (measles, mumps and
rubella). "While I support any effort to discover the reason a child has autism, current scientific data indicate that vaccines are not the cause," Dr. Cook said.

Autism manifests itself in the first three years of life, which is the
same time a child is being vaccinated, but timing is the only link. A study in the British medical journal Lancet found similar autism rates among children who received the MMR vaccine and those who had not. A report commissioned by Britain's Medical Research Council and released this week found that there was no link between MMR and autism or bowel disorders.

The American Academy of Pediatrics supports aggressive research into the causes, treatment and prevention of autism as many questions remain. The perceived increase in autism cases could be attributed to a number of factors, and additional study is needed.

Vaccines are developed through rigorous research designed to ensure safe and effective products. These products are then subjected to another level of intense scrutiny in order to assure that recommendations about immunization practices and procedures reflect the best available science.

Once approved for use, there is a robust system of checks and balances that monitors the safety and efficacy of vaccines.

A child's chance of being harmed by an infectious disease like measles or mumps is far greater than any risk of being harmed by the vaccine. These diseases have not been eliminated, only kept at bay through widespread childhood immunization. Measles, for example, can lead to pneumonia or an infection of the brain and can cause death. Mumps can cause an infection in the lining of the brain and death.

To help inform parents about the benefits and risks of vaccines, the
American Academy of Pediatrics has developed brochures that are distributed by pediatricians. Vaccine information can also be obtained on the AAP website: www.aap.org. Parents should also talk to their pediatrician.
###
back to top



American Public Health Association (regarding April 6 Burton hearing).

Vaccines are Integral Component of Good Public Health

In response to today's U.S. House Government Reform Committee hearing on autism and infant vaccines, the American Public Health Association (APHA) expresses its strong and continued support for universal immunization against vaccine-preventable diseases.

"We strongly recommend that health care providers and parents continue to immunize their children, since the health of all children could be seriously jeopardized by a drop in immunization rates," said Mohammad N. Akhter, MD, MPH, executive director of APHA. "Furthermore, APHA advocates that efforts be made to ensure the highest safety standards in vaccine development, manufacture, and distribution, in order to limit adverse effects. These efforts must include research directed to the elimination of the rare unfavorable reactions to immunizations."

In spite of the most exhaustive scientific research, a small number of
reactions may still be experienced. These occasions, like any adverse health effect, are truly devastating for those affected. However, it is important to remember that serious consequences will result for many more people if we reduce our immunization programs. Vaccine-preventable diseases can cause widespread blindness, deafness, brain damage, mental retardation, heart defects, sterility, miscarriage, paralysis and death.

The American Public Health Association, the largest and oldest
organization of public health professionals, represents more than 50,000 members from over 50 public health occupations and strongly supports efforts to eliminate communicable diseases through immunizations and other means around the world.
###
back to top


Date April 06, 2000
Time 06:30 PM - 07:00 PM
Station NBC-TV
Location Network
Program NBC Nightly News

Tom Brokaw, anchor:
Now, our special "Lifeline" series: best medicine.

Tonight, sorting out troubling questions about a heartbreaking disease for children and their families: autism. A hearing in Washington today to address fears that routine childhood vaccinations might somehow be to blame. 

Here's NBC's Robert Hager.

Robert Hager reporting:
Gina Smith has three completely healthy children, and a  fourth, Jacob, who's autistic. 

Gina Smith (Mother): He will never play on a sports' team. He will never be able to go to an amusement park. He does--he won't be able to go to birthday parties. The stimulation is more then he can handle. 

Hager: Autism is a severe developmental disorder. Victims seem isolated from the world around them and for unknown reasons the number of cases reported among children is growing fast, now more than fifty thousand. Today, parents appealed to Congress for help. Gina Smith came from Louisiana to tell how Jacob's problem seemed to come on suddenly at sixteen months. 

Smith: (Clip from video of congressional testimony) The light behind his eyes was replaced with a blank, lost, bewildered stare.

Hager: Kenneth Curtis came from Maryland to tell about his son. 

Kenneth Curtis (Father): (Clip from video of congressional testimony) I know there are things that my son wants to say to me, and as he gets older I can--I can look into his eyes and I can see the frustration and the confusion.

Hager: The hearing chaired by Congressman Dan Burton who has a personal reason for finding answers: an autistic grandson. And Burton believes it might have been triggered by the routine immunization shots all children get for measles, mumps, rubella and more. A controversial theory, but some feel it needs investigation. (Visual of a bottle of Measles, Mumps, Rubella virus serum).

Bernard Rimland (Autism Research Institute): I don't necessarily believe that children should not be vaccinated. I think that much more research needs to be done on the safety of the vaccines. I think much more judgment needs to be exercised in the using of vaccines.

Hager: But the government's two pre-eminent health agencies, the Centers for Disease Control and the National Institutes for Health, told Congress today there's no evidence at all to link autism and vaccinations. Said autism seems to be inherited and seems to develop before birth, even when it doesn't appear until months after birth.

Dr. Paul Offit (University of Pennsylvania): The scientific study that has been done has shown us clearly that vaccines don't cause autism.

Hager: But doctors admit they are a long way from knowing what does cause the disorder. Not only that but there is no known cure, even as government spending to find out more has quadrupled in recent years. A long way from answers for Congressman Burton, for parents like Gina Smith, her son Jacob, and tens of thousands more with this baffling disorder.

Robert Hager, NBC News, Washington.
###
back to top


"After Disputes, House Panel Asks for Study of a Vaccine"
New York Times (www.nytimes.com) (04/07/00) P. A19; Hilts, Philip J.

Leaders of the House Government Reform and Oversight Committee have agreed to ask the Department of Health and Human Services to study the possible link between vaccination and autism.  Several witnesses spoke at Thursday's hearing, which was called by the committee's chairman, Rep. Dan Burton (R-Ind.), whose granddaughter has autism.  Current research has not shown any connection between the onset of autism and the measles-mumps-rubella (MMR) vaccine, but many parents describe their children suddenly exhibiting symptoms of the disorder after vaccination.  Autism is characterized by a failure to speak, withdrawal from social behavior, and repetitive motions.  Rep. Henry Waxman (D-Calif.) warned that it is important not to scare 
parents into mistrusting vaccines because that could result in deaths from diseases that are preventable.  While a recent study from Dr. Brent Taylor of the Royal Free and University College 
Medical School in London refutes previous research that suggested the MMR vaccine may cause some cases of autism, some people are concerned by rising rates of autism in several nations--including the United States--although that could be, in part, the result of increased publicity and awareness of the condition.
###
back to top



Press release: By Parents of Kids with Infectious Diseases.

National Parent Organization Underscores Commitment to Helping Children Live Stronger and Healthier Lives

WASHINGTON, April 6 /PRNewswire/ -- The national parent advocacy organization, PKIDs (Parents of Kids with Infectious Diseases), is committed to protecting our nation's children against diseases that have life-long effects on their health and development.  In response to a U.S. House Government Reform Committee hearing on autism (Thursday, April 6), PKIDs voices its support for more resources for autism research and stresses that there is no scientific evidence linking autism to immunization.

"There is a long way to go in understanding autism.  As a nation, we
cannot ignore the need for research to find a cure for this severe and very prevalent neurological disorder," said Trish Parnell, director of PKIDs. 

"Autism affects more than 400,000 families and costs the nation over
13 billion dollars a year -- it deserves as much public attention and
research as other childhood diseases."

Although autism is currently the third most common developmental
disorder, it receives less than five percent of the funding for research of other childhood diseases, like multiple sclerosis and cystic fibrosis.  Funding for research into diseases such as autism is an integral part of finding a cure.

In hopes of improving the quality of children's health across the
country, PKIDs lends its support to H.R. 3301, the  "Children's Health Research and Prevention Amendments of 1999" that would amend the Public Health Service Act in regards to children's health.

NO SCIENTIFIC EVIDENCE LINKING IMMUNIZATION TO AUTISM

While PKIDs advocates for additional resources for autism research, it does not condone the spread of false and misleading information linking autism to childhood vaccination.  PKIDs strongly encourages parents to continue immunizing their children with scientifically proven safe and effective vaccines.

"Today's high immunization rates are what is protecting us from
outbreaks of measles, rubella, diphtheria and polio," said Dr. Ed Marcuse, Director, Medical Services at Seattle's Children's Hospital and Regional Medical Center. "If we stopped vaccinating, costly outbreaks of these vaccine-preventable diseases would return as surely as spring follows winter with devastating consequences for some families."

Over the past 50 years, vaccines have gained control over or virtually  eliminated diseases that used to be very common in the U.S., including measles, diphtheria, polio, smallpox, rubella, Hib meningitis and mumps. But, other diseases such as hepatitis B, varicella and pneumococcal meningitis are still common, resulting in serious illness for many families.  In fact, even in the U.S., where immunization rates are the highest, approximately 1 million pre-school children are not adequately protected against potentially
disabling or fatal diseases that can be prevented by immunization.

For more information, please call 877-55-PKIDS or log onto
http://www.pkids.org.
###
back to top



Los Angeles Times
Copyright 2000 Times Mirror Company
Los Angeles Times

April 7, 2000, Friday, Home Edition
SECTION: Part A; Page 26; National Desk

Autism-Vaccine Link Raised in Hearing; Medicine: Psychologist Tells House Panel that Steep Rise in Disorder may Stem from Immunization Campaign, a Theory Hotly Contested by Other Experts.

Byline: Sunny Kaplan, Times Staff Writer

Declaring that autism has reached "epidemic" proportions, the head
of San Diego's Autism Research Institute testified Thursday at a
hearing on Capitol Hill that the disease may be linked to routine vaccines that millions of children are required to receive--a theory that is disputed by other medical experts.

Bernard Rimland, a research psychologist who has studied the symptoms and possible causes of autism for 35 years, joined other
scientists, public health officials and parents of autistic children to
discuss the increasing rates of autism throughout the country.

The hypothesis that the disease may be linked to vaccines is of particular controversy, and many public health officials argue that it is
"extremely unlikely" there is a causal relationship.

"To date there has been no convincing scientific evidence that links any vaccine to autism or any other kind of behavioral disorder," said Dr. Thomas R. Reardon, president of the American Medical Assn., in testimony submitted to the House Committee of Government Reform, which called the hearing.

But Rick Rollins, a co-founder of an autism research center at UC Davis and the father of an autistic 9-year-old son, said a California state study released last spring that showed a 273% increase in autism over an 11-year period is a strong argument for further research into a possible vaccine-autism connection.

"There is not one single thing here that may be the cause. This is a complicated disease," said Rollins, a former secretary of the California Assembly. "But we need to really accelerate good scientific research and funding."

Autism is a developmental disorder marked by social isolation,
uncommunicativeness and strange repetitive behaviors that can range from mild to profound. It is three to four times more common in boys than in girls and is usually apparent by age 3. No cure exists, but some problems can be alleviated with intensive behavioral therapy.

Candace Pert, a research professor in the department of physiology at Georgetown University School of Medicine in Washington, said that, while recent research has shown a genetic contribution to autism, the findings suggest that no more than 20% of autism cases are genetic.

Some proponents of the theory that vaccines may cause autism say the sheer number of vaccines that children receive--at least two dozen doses before they enter first grade--may overload a young child's immune system. Some parents of autistic children point anecdotally to the measles-mumps-rubella (MMR) vaccine as the most likely culprit, saying that their children were "normal" until they received that vaccine, which is typically administered from age 12 months to 15 months.

Rimland's findings mirror that hypothesis. "Autism starting at 18 months rose very sharply in the mid-1980s, when the MMR vaccine came into wide use," he said.

Dr. Michael Goldberg, a Los Angeles pediatrician and director of the Neuro Immune Dysfunction Syndrome Research Institute,
hypothesizes that vaccines do not necessarily cause autism but serve as catalysts for the disease in children who are genetically predisposed to it.

Goldberg said that the measles-mumps-rubella vaccine can serve as a common trigger for autism because it is highly "immunogenic,"
meaning that it stimulates the immune system.

Yet another hypothesis is that mercury, which is often used as a
preservative in vaccines, may be related to autism. The presence of
heavy-metal toxicity, notably mercury, has been found in some autistic children.

Environmental toxins may also be a contributing factor, as is pointed out in a study recently finished, but yet to be released, conducted by the federal Agency for Toxic Substances and Disease Registry on Brick Township, N.J., a community north of Atlantic City where the
childhood prevalence of autism is reputed to be 1 in 200.

Rep. Dan Burton (R-Ind.), who chairs the committee that called the hearing, has a 3-year-old grandson whose autism he attributes to
vaccination. But Burton said he is "not against vaccinations" and doesn't think that every autistic child acquires autism after receiving
childhood immunizations.

In a news conference preceding the hearing, Burton said that the rise in the disease is not just an "aberration."

The federal Department of Health and Human Services "says there is no correlation between shots and the dramatic rise in autism. I am
very concerned about the closed-minded attitude of this agency," Burton said. He continued to say that he intends to subpoena people from the pharmaceutical industry to appear before his committee to explain the dramatic increase in autism.

Rep. Henry A. Waxman of Los Angeles, the committee's ranking Democrat, agreed that vaccines "shouldn't be off the table" as a theory for the increase but said "we must not get ahead of science or raise a false alarm."

Waxman also criticized the proceedings as skewed toward proponents of the theory that vaccines cause autism.
###
back to top


The Philadelphia Inquirer
April 7, 2000, Friday

Parents tell congressional committee that vaccine sickened their children

BYLINE: By Huntly Collins

Distraught parents told a congressional committee Thursday
that a vaccine aimed at preventing measles, mumps and
rubella likely caused their children to become autistic.

But various experts, including officials from the U.S. Centers for Disease Control and Prevention, said there was no scientific evidence to support the alleged link between autism and the so-called MMR vaccine.

They warned that such false information could lower immunization rates and leave the nation vulnerable to a measles epidemic like the one that killed 123 children, including nine in Philadelphia, in 1990-91.

"If, as a result of reading about this hearing, some parents choose to
withhold or delay vaccines for their children, their tragedy could be
profound," said Dr. Paul Offit, chief of infectious disease at Children's Hospital of Philadelphia and a member of the CDC advisory panel that decides what vaccines will be recommended for American children.

The debate came during a daylong hearing in Washington before the House Committee on Government Reform, chaired by Rep. Dan
Burton, R.-Ind.

Burton, who also has been holding hearings on the military's controversial anthrax vaccine, said his grandson, Christian, became autistic after getting the MMR vaccine.

"I can't believe that's just a coincidence," he said, adding that
scientists who say that autism is a genetic disorder are "just nuts."

Burton came under fire from Rep. Henry Waxman, D., Calif., the committee's ranking minority member, for using the committee hearing as a bully pulpit to promote an unproven _ and potentially dangerous _ notion.

"This hearing was called to establish a point of view _ a point of view
established by the chairman," Waxman said.

The MMR vaccine, developed by Merck & Co., has become the cornerstone of pediatric health in the United States. It involves one shot that protects children against three diseases that used to be among the leading causes of death and disability. Typically, babies are vaccinated at 12 months and given a booster when they turn 4.

Two developments have prompted the notion that the MMR vaccine may cause autism. One is an apparent rise in the prevalence of autism, from about 5 cases per 10,000 births to 12 cases per 10,000 births between 1966 and 1985, according to federal officials.

But Coleen Boyle, head of the CDC's disabilities branch, told the committee that the apparent rise in the autism rate may be due to
expanded definitions of autism and greater public awareness of the disorder rather than an actual increase in the incidence of the problem.

Another factor fueling the debate is a controversial small study by Andrew Wakefield, a British gastroenterologist, who found that 8 of 12 children developed autism soon after getting the MMR vaccine.

Wakefield defended his work before the committee Thursday, but his findings were rebutted by Dr. Brent Taylor, another British physician, who studied 498 children with autism in North London and found no connection with the MMR vaccine.

He said Wakefield's work had had "a major effect" on public confidence in the vaccine, with immunization rates in England dropping from about 90 percent in 1995 to 75 percent last year. "The same thing could happen in the United States," Taylor said.

Autism is a brain-based developmental disorder in which children typically engage in repetitive behaviors such as rocking; speak little or not at all, and make little eye contact, seemingly immersed in their own private world. The cause of the disorder is not clear, but numerous genes have been implicated.

During the hearing, Burton assailed Offit's credibility, suggesting that
the infectious disease expert from Children's Hospital shouldn't be
allowed to sit on the CDC's vaccine advisory board because he is currently developing a vaccine against rotavirus, which causes severe
diarrhea among children, in collaboration with Merck.

But Dr. Benjamin Schwartz, a CDC vaccine official, said the 12-member board required scientists to disclose any financial ties that might give the appearance of a conflict. He said the agency sought out experts like Offit because they are the most knowledgeable about infectious disease and the vaccines to prevent them.

Coverage of the hearing from the Philadelphia Inquirer

(c) 2000, The Philadelphia Inquirer.
Copyright 2000 Knight Ridder/Tribune News Service
Knight Ridder/Tribune News Service

Visit Philadelphia Online, the Inquirer's World Wide Web site, at
http://www.philly.com/mld/philly/
###

back to top